UK‑396082
CAS No. : 400044-47-5
| Size | Price | Stock |
|---|---|---|
| 1mg | $641 | In-stock |
| 5mg | $1548 | Get quote |
| 10mg | $2167 | Get quote |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
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| Cat. No. : | HY-122052 |
| M.Wt: | 239.31 |
| Formula: | C12H21N3O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
UK‑396082 is a potent thrombin activated fibrinolytic inhibitor (TAFI) inhibitor. UK‑396082 increases plasmin activity and induces a parallel decrease in ECM levels. UK‑396082 can be used in research of chronic kidney disease (CKD)[1].
In Vitro:UK‑396082 (0-1000 nM; NRK52E cells; 96 h) induces TAFI activity in a dose-dependent manner[1].
UK‑396082 (500 nM; 24 h) increases plasmin activity in NRK52E cells (+109%) and NRK49F fibroblasts (+38.3%)[1].
UK‑396082 (500 nM; 24 h) has a 46% reduction in ECM levels[1].
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