25-Hydroxytachysterol3


CAS No. : 39932-44-0

39932-44-0
Price and Availability of CAS No. : 39932-44-0
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1mg $500 In-stock
5mg $1108 In-stock
10mg $1664 In-stock
25mg $3328 In-stock
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Cat. No. : HY-77278
M.Wt: 400.64
Formula: C27H44O2
Purity: >98 %
Solubility:
Introduction of 39932-44-0 :

25-Hydroxytachysterol3 is the metabolite of Vitamin D3 (HY-15398). 25-Hydroxytachysterol3 inhibits the proliferation of epidermal keratinocytes and dermal fibroblasts, stimulates the expression of differentiation- and antioxidant-related genes in keratinocytes. 25-Hydroxytachysterol3 activates vitamin D receptor (VDR) and aryl hydrocarbon receptor (AhR), liver X receptor α/β (LXR α/β) and peroxisome proliferator-activated receptor γ (PPARγ), stimulates the expression of CYP24A1[1]. In Vitro:25-Hydroxytachysterol3 (25(OH)T3) (0.1-100 μM; 24-48 h) inhibits the proliferation of epidermal keratinocytes and dermal fibroblasts[1].
25-Hydroxytachysterol3 (0.1-100 μM; 24 h) stimulates the expression of genes involved in keratinocyte differentiation and antioxidative pathways[1].

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