| Size | Price | Stock |
|---|---|---|
| 1mg | $500 | In-stock |
| 5mg | $1108 | In-stock |
| 10mg | $1664 | In-stock |
| 25mg | $3328 | In-stock |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-77278 |
| M.Wt: | 400.64 |
| Formula: | C27H44O2 |
| Purity: | >98 % |
| Solubility: |
25-Hydroxytachysterol3 is the metabolite of Vitamin D3 (HY-15398). 25-Hydroxytachysterol3 inhibits the proliferation of epidermal keratinocytes and dermal fibroblasts, stimulates the expression of differentiation- and antioxidant-related genes in keratinocytes. 25-Hydroxytachysterol3 activates vitamin D receptor (VDR) and aryl hydrocarbon receptor (AhR), liver X receptor α/β (LXR α/β) and peroxisome proliferator-activated receptor γ (PPARγ), stimulates the expression of CYP24A1[1].
In Vitro:25-Hydroxytachysterol3 (25(OH)T3) (0.1-100 μM; 24-48 h) inhibits the proliferation of epidermal keratinocytes and dermal fibroblasts[1].
25-Hydroxytachysterol3 (0.1-100 μM; 24 h) stimulates the expression of genes involved in keratinocyte differentiation and antioxidative pathways[1].
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