16,16-Dimethyl prostaglandin E2


CAS No. : 39746-25-3

(Synonyms: 16,16-dimethyl PGE2)

39746-25-3
Price and Availability of CAS No. : 39746-25-3
Size Price Stock
26.28 mM * 1 mL in Methyl acetate $320 In-stock
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Cat. No. : HY-106420
M.Wt: 380.52
Formula: C22H36O5
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 39746-25-3 :

16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) is an orally active vertebrate Hematopoietic stem cells (HSCs) homeostasis critical regulator. 16,16-Dimethyl prostaglandin E2 can act through EP2/EP4 and has an interaction with the Wnt pathway[1][2]. In Vivo: 16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2; 10 μg/kg; i.p.; every 12 hours; for 8 days) rescues the exacerbated DSS colitis phenotype of Tpl2IMF-KO mice and restores epithelial proliferation and structure[2].

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