(±)-Befunolol
CAS No. : 39552-01-7
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| Cat. No. : | HY-101752 |
| M.Wt: | 291.34 |
| Formula: | C16H21NO4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
(±)-Befunolol is a β-adrenoceptor blocking agent. IC50 & Target: Adrenoreceptor[1] In Vitro: A β-adrenoceptor blocking agent, Befunolol, is found to has intrinsic sympathomimetic activities in isolated right atria, trachea and taenia caecum of guinea pig (intrinsic activities are 0.22-0.28). The pD2-values of Befunolol estimated in the isolated organs are significantly different from its pA2-values against isoprenaline. Befunolol interacts with the beta-adrenoceptor where there may be two different sites: one site for agonistic action and the other for competitive antagonistic action. The intrinsic activity of Befunolol may be equal to its selectivity for both the sites[1].
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