L-Alanyl-L-glutamine


CAS No. : 39537-23-0

(Synonyms: Alanyl-glutamine)

39537-23-0
Price and Availability of CAS No. : 39537-23-0
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Cat. No. : HY-W014102
M.Wt: 217.22
Formula: C8H15N3O4
Purity: >98 %
Solubility: DMSO : < 1 mg/mL (ultrasonic);H2O : 50 mg/mL (ultrasonic)
Introduction of 39537-23-0 :

L-Alanyl-L-glutamine, a glutamine dipeptide, is benefit for the antioxidant system, attenuating inflammation, and may modulate the heat shock protein (HSP) response in catabolic situations[1]. In Vitro: L-Alanyl-L-glutamine (2 mM; 24 hours) partially or fully attenuates chronic insulin secretion, and IR-β and COX IV levels which are decreased when β-cells were exposed to macrophages following stimulation in vitro (IMMs)[1].
L-Alanyl-L-glutamine -dependent β-cell protection mediated by coordinated effects on the glutamine-GSH axis, and the HSP pathway, maintenance of mitochondrial metabolism and stimulus-secretion coupling essential for insulin release[1].

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