MitoBloCK-10
CAS No. : 394694-98-5
| Size | Price | Stock |
|---|---|---|
| 500μg | $50 | Get quote |
| 1mg | $80 | In-stock |
| 5mg | $200 | In-stock |
| 10mg | $300 | In-stock |
| 25mg | $480 | In-stock |
| 50mg | $672 | In-stock |
| 100mg | $940 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-115467 |
| M.Wt: | 293.27 |
| Formula: | C12H8FN3O3S |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
MitoBloCK-10 (MB-10) is the first small molecule modulator to attenuate protein-associated motor (PAM) complex activity. MitoBloCK-10 (MB-10) inhibits Tim44 (C-terminal domain) binding to the precursor and to Hsp70[1].
In Vitro: MB-10 (100 μM) is a potential attenuator of protein import into mitochondria[1].
MB-10 inhibits the import of substrates that use the TIM23 import pathway[1].
MB-10 (0-100 μM) inhibits protein import into mammalian mitochondria[1].
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