KH064
CAS No. : 393569-31-8
| Size | Price | Stock |
|---|---|---|
| 500μg | $45 | Get quote |
| 1mg | $70 | In-stock |
| 5mg | $260 | In-stock |
| 10mg | $450 | In-stock |
| 25mg | $890 | In-stock |
| 50mg | $1420 | In-stock |
| 100mg | $2200 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-11059 |
| M.Wt: | 487.63 |
| Formula: | C31H37NO4 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
KH064, a D-tyrosine derivative, is an orally active, potent secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 29 nM for human nonpancreatic secretory PLA2 isoform IIa (hnpsPLA2-IIa). KH064 has anti-inflammatory activity[1]. In Vivo: KH064 (compound 2b; oral; 5 mg/kg/day; on Days 10-13 after inoculation with arthritogen) shows substantial inhibition of the oedema. Drug-treated rats shows mild capsular oedema and minimal infiltration of macrophages into the red pulp[1].
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