MCHR1 antagonist 1
CAS No. : 391610-37-0
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| Cat. No. : | HY-U00353 |
| M.Wt: | 557.59 |
| Formula: | C28H33F2N5O5 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
MCHR1 antagonist 1 is a selective antagonist of melanin concentrating hormone-1 (MCH1) receptor, with a Kb of 1 nM and a Ki of 4 nM at human MCH1, and may be used to reduce the body mass.
IC50 & Target: Kb: 1 nM (Human MCH1)[1]
Ki: 4 nM (Human MCH1)[1]
In Vitro: MCHR1 antagonist 1 shows potent activities against melanin concentrating hormone-1 receptor, but less potent against human MCH1, NPY1, NPY5, GALR1, GALR2, GALR3, and rat 5HT2C receptors, with Kis of >50000 nM[1].
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