Cephradine


CAS No. : 38821-53-3

(Synonyms: Cefradine; SQ-11436)

38821-53-3
Price and Availability of CAS No. : 38821-53-3
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500mg $40 In-stock
1g $60 In-stock
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Cat. No. : HY-B1156
M.Wt: 349.40
Formula: C16H19N3O4S
Purity: >98 %
Solubility: DMSO : ≥ 3.6 mg/mL;H2O : 8.33 mg/mL (ultrasonic)
Introduction of 38821-53-3 :

Cephradine (Cefradine) is a broad-spectrum and orally active cephalosporin. Cephradine is active against both gram-positive and gram-negative pathogens. Cephradine is effective in eradicating most penicillinase-producing organisms. Cephradine has been used in the research of genitourinary, gastrointestinal and respiratory tract infections, and in infections of the skin and soft tissues. Cephradine blocks solar-ultraviolet induced skin inflammation through direct inhibition of TOPK[1][2][3]. IC50 & Target: Bacteria[1].
Antibiotic[1].
TOPK[3]. In Vitro: Cephradine (0~8 μg/mL; 12 hours) makes bacterial viability rapidly increased at antibiotic concentrations below the MIC (minimum inhibitory concentration) of 0.70 µg/mL at both pH 7.4 and pH 5.5[4]. In Vivo: Cephradine (25 mg/kg; s.c.; 11 days) reduces the bacterial density and counts in the abscesses[4].

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