Neuropeptide W-23 (human)
CAS No. : 383415-79-0
(Synonyms: NPW-23)
| Size | Price | Stock |
|---|---|---|
| 1mg | $150 | In-stock |
| 5mg | $450 | In-stock |
| 10mg | $650 | In-stock |
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| Cat. No. : | HY-P1035 |
| M.Wt: | 2584.01 |
| Formula: | C119H183N35O28S |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 50 mg/mL |
Neuropeptide W-23 (human) (NPW-23), the active form of Neuropeptide W, is an endogenous agonist of NPBW1 (GPR7) and NPBW2 (GPR8)[1].
IC50 & Target:NPBW1, NPBW2[1]
In Vitro: Neuropeptide W-23 (human) (NPW-23) increases the ICa,L in transfected human embryonic kidney 293 cells and VSMCs via GPR7[1].
Neuropeptide W-23 (human) increases the expression of pan phospho-PKC, intracellular diacylglycerol level, and the second messenger catalyzed by PLC[1].
In Vivo: Neuropeptide W-23 (human) (NPW-23) (0.3-3.0 nM; intracerebroventricular injection; 2 μL) increases total behavioral activity, including locomotion and grooming in conscious rats[2].
Neuropeptide W-23 (human) (NPW-23) (2-8 nM; i.c.v.; 10 μL) shows anorexigenic effect in rats[3].
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