Minoxidil
CAS No. : 38304-91-5
(Synonyms: U10858)
| Size | Price | Stock |
|---|---|---|
| 500mg | $55 | In-stock |
| 1g | $66 | In-stock |
| 5g | $143 | In-stock |
| 10 g | Get quote | |
| 50 g | Get quote | |
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| Cat. No. : | HY-B0112 |
| M.Wt: | 209.25 |
| Formula: | C9H15N5O |
| Purity: | >98 % |
| Solubility: | Ethanol : 7.14 mg/mL (ultrasonic);H2O : 1 mg/mL (ultrasonic;warming;heat to 50°C);DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C) |
Minoxidil (U10858) is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil is also a potent inhibitor of soybean lipoxygenaseare with an IC50 of 20 μM[1][2][3]. IC50 & Target:IC50: 20 μM (soybean lipoxygenaseare)[1]; ATP-sensitive potassium channel[2] In Vitro: Minoxidil (1-00 μM; 24 hours; RAMEC cells) treatment shows very low cytotoxicities in the whole area of concentrations examined (from 1 μM to 100 μM)[1]. In Vivo: Minoxidil (0.01 mmoL/kg body weight; intraperitoneal injection; for 3.5 hours; fisher 344 rats) treatment inhibits carrageenan-induced rat paw oedema with an inhibitory potency (49%)[1].
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