PK11000
CAS No. : 38275-34-2
| Size | Price | Stock |
|---|---|---|
| 250mg | $50 | In-stock |
| 1g | $150 | In-stock |
| 5g | $440 | Get quote |
| 10 g | Get quote | |
| 50 g | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-U00447 |
| M.Wt: | 236.63 |
| Formula: | C6H5ClN2O4S |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic);H2O : 25 mg/mL (ultrasonic) |
PK11000 is an alkylating agent, and stabilizes the DNA-binding domain of both WT and mutant p53 proteins by covalent cysteine modification without compromising DNA binding. PK11000 has anti-tumor activities[1].
IC50 & Target: p53[1]
In Vitro: PK11000 (0-120 μM, 24 h) mildly inhibits mutant p53 cancer cells[1].
PK11000 (0-50 μM, 5 d) shows anti-proliferation effects of breast cell lines[2].
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