Zinterol (hydrochloride)
CAS No. : 38241-28-0
(Synonyms: MJ 9184 (hydrochloride))
| Size | Price | Stock |
|---|---|---|
| 1mg | $155 | In-stock |
| 5mg | $310 | In-stock |
| 10mg | $500 | In-stock |
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| Cat. No. : | HY-14304A |
| M.Wt: | 414.95 |
| Formula: | C19H27ClN2O4S |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Zinterol hydrochloride (MJ 9184 hydrochloride) is a potent and selective β2-adrenoceptor agonist[1]. Zinterol hydrochloride increases ICa in a concentration-dependent manner with an EC50 of 2.2 nM[2]. Zinterol hydrochloride induces ventricular arrhythmias in conscious heart failure rabbits[3]. IC50 & Target: β2-adrenoceptor[1] In Vivo: Zinterol (2.5 μg/kg i.v. bolus over 5 s) leads to ventricular arrhythmias including premature ventricular complexes (PVCs) and runs of ventricular tachycardia (VT) in heart failure (HF) rabbits. Zinterol at a lower dose (1 μg/kg i.v, n=4) does not induce ventricular arrhythmias in HF rabbits[3].
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