ML367


CAS No. : 381168-77-0

381168-77-0
Price and Availability of CAS No. : 381168-77-0
Size Price Stock
5mg $50 In-stock
10mg $80 In-stock
25mg $160 In-stock
50mg $250 In-stock
100mg $400 In-stock
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Cat. No. : HY-122198
M.Wt: 334.32
Formula: C19H12F2N4
Purity: >98 %
Solubility: DMSO : ≥ 125 mg/mL
Introduction of 381168-77-0 :

ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization, acts as a probe molecule that has low micromolar inhibitory activity. ML367 blocks DNA repair pathways, suppresses general DNA damage responses including RPA32-phosphorylation and CHK1-phosphorylation in response to UV irradiation[1]. IC50 & Target: ATAD5[1] In Vitro: ML367 (0-40 μM, 16 hours) inhibits FLAG-ATAD5 stabilization in HEK293T cells in the presence or absence of 20 μM 5-FUrd[1].

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