CMPDA
CAS No. : 380607-77-2
| Size | Price | Stock |
|---|---|---|
| 5mg | $390 | In-stock |
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| Cat. No. : | HY-12508 |
| M.Wt: | 376.53 |
| Formula: | C16H28N2O4S2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
CMPDA is a positive allosteric modulator of AMPA receptors with EC50s of 45.4 ± 4.2 nM/63.4 ± 5.6 nM for GluA2i/GluA2o receptor. IC50 value: 45.4 ± 4.2 nM/63.4 ± 5.6 nM(GluA2i/GluA2o) [1] Target: AMPAR modulator CMPDA was nearly equipotent at modulating the two isoforms of GluA2 receptors, whereas CMPDB displayed a modest preference for the flip splice variant. Similar to CX614, CMPDA slowed the rate of deactivation of GluA2o receptors approximately 2-fold but had no effect on GluA2i receptor deactivation [1].
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