(+)-Columbianetin (Standard)
CAS No. : 3804-70-4
(Synonyms: (S)-Columbianetin (Standard))
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| Cat. No. : | HY-N0363R |
| M.Wt: | 246.26 |
| Formula: | C14H14O4 |
| Purity: | >98 % |
| Solubility: |
(+)-Columbianetin (Standard) is the analytical standard of (+)-Columbianetin (HY-N0363). This product is intended for research and analytical applications. (+)-Columbianetin ((S)-Columbianetin) acts as an inhibitor of JNK/ERK. (+)-Columbianetin inhibits UVA-induced phosphorylation of JNK and ERK, reduces the production of MMP-1, reverses UVA-induced Collagen (HY-NP003) degradation, and alleviates UVA-mediated inhibition of Smad2/3 phosphorylation and translocation. (+)-Columbianetin regulates the AP-1 and ASK1-MAPK signaling pathways, inhibits the production of ROS and blocks sub-G1 cell cycle arrest. (+)-Columbianetin is applicable to research related to skin aging[1][2].
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