UK-432097


CAS No. : 380221-63-6

380221-63-6
Price and Availability of CAS No. : 380221-63-6
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Cat. No. : HY-107046
M.Wt: 777.87
Formula: C40H47N11O6
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 380221-63-6 :

UK-432097 is a highly potent and selective A2AAR agonist with a pKi of 8.4 for human A2AAR. UK-432097 has anti-inflammatory and anti-aggregatory properties. UK-432097 has the potential for COPD (Chronic Obstructive Pulmonary Disease) research[1][2][3]. IC50 & Target: pKi: 8.4 (A2AAR)[1] In Vitro: UK-432097 has an EC50 value of 0.66 nM using CHO cells expressing human WT A50AR[1].
UK-432097 (0.01, 0.1, 1, 10, 100, 1000 nM; pretreated for 2 hours) significantly increases cAMP accumulation in CHO-A2A cells[3].

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