Nemonoxacin
CAS No. : 378746-64-6
(Synonyms: TG-873870)
| Size | Price | Stock |
|---|---|---|
| 1mg | $220 | In-stock |
| 5mg | $465 | In-stock |
| 10mg | $740 | In-stock |
| 25mg | $1320 | In-stock |
| 50mg | $1960 | In-stock |
| 100mg | $2950 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-14956 |
| M.Wt: | 371.43 |
| Formula: | C20H25N3O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 2 mg/mL (ultrasonic;warming;heat to 60°C) |
Nemonoxacin (TG-873870) is an orally active and potent broad-spectrum antibiotic. Nemonoxacin shows good inhibitory activity against different species of staphylococci, streptococci, and enterococci, Neisseria gonorrhoeae, and Haemophilus influenza. Nemonoxacin can be used in the study of bacterial infections and community-acquired pneumonia[1][2][3].
IC50 & Target:Bacterial[1][2][3].
In Vitro:Nemonoxacin (0-5.51 µM; 24 h) shows good antibacterial activity in vitro[1].
In Vivo:Nemonoxacin (p.o.; 15 min and 6 h after infection) shows potent and broad-spectrum in vivo activity against both Gram-positive (S. aureus, S. capitis, S. pneumonia and E. faecalis) and Gram-negative (E. coli) isolates[2].
Nemonoxacin (p.o.; 6, 12 and 24 h after infection) shows potent activities towards (2.5, 5, 10, 20 mg/kg) S. pneumonia 0613 (PRSP) and (10, 20, 40, 80 mg/kg) K. pneumonia 0607 infections in mouse pulmonary infection model[2].
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