Enmein
CAS No. : 3776-39-4
| Size | Price | Stock |
|---|---|---|
| 1mg | $624 | In-stock |
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| Cat. No. : | HY-N5028 |
| M.Wt: | 362.42 |
| Formula: | C20H26O6 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Enmein is isolated from I. serra with immunosuppressive effect[1]. In Vitro: Enmein shows significant inhibitory effect toward K562 with an IC50 value ranging from 3.2 μg/ml to 8.2 μg/ml[2]. Enmein (3.13-25 μg/ml; 48 hours) has inhibitory effect on lymphocytes with significant difference within concentration from 6.25 μg/ml to 25 μg/ml[1]. Enmein (5.5-22 μg/ml; 48 hours) causes the percentage of S stage cells decreased from 19% to 6%, causes the percentage of G2/M stage cells to decrease from 2% to 0.4%[1]. In Vivo: Enmein (inject to ear; 6.52-13.04 mg/kg; 5 days) inhibits the xylene-induced ear swelling and inhibits IL-2 expression[1].
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