| Size | Price | Stock |
|---|---|---|
| 5mg | $90 | In-stock |
| 10mg | $145 | In-stock |
| 25mg | $270 | In-stock |
| 50mg | $435 | In-stock |
| 100mg | $700 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-124571 |
| M.Wt: | 228.31 |
| Formula: | C10H16N2O2S |
| Purity: | >98 % |
| Solubility: | DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C) |
ZQ-16 is a potent and selective GPR84 agonist with an EC50 value of 0.213 μM. ZQ-16 has no activity on the other free fatty acid receptors (FFARs), including GPR40, GPR41, GPR119 and GPR120[1].
In Vitro:ZQ-16 induces calcium response in a dose-dependent manner, with an EC50 value of 0.213 μM[1].
ZQ-16 also induces dose-dependent reduction of Forskolin-stimulated cAMP accumulation in HEK293 cells expressing GPR84 with an EC50 value of 0.134 μM[1].
ZQ-16 (10 μM; 5 min) also induces phosphorylation of ERK1/2 in GPR84-expressing HEK293 cells[1].
ZQ-16 induces GPR84 desensitization, internalization, and β-arrestin2 recruitment. ZQ-16 induced a dose-dependent recruitment of β-Arrestin2 towards GPR84 in HEK293 cells expressing both proteins with an EC50 value of 0.597 μM[1].
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