Totrombopag
CAS No. : 376592-42-6
| Size | Price | Stock |
|---|---|---|
| 1mg | $420 | In-stock |
| 5mg | $995 | In-stock |
| 10mg | $1350 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-14756 |
| M.Wt: | 466.49 |
| Formula: | C25H22N8O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Totrombopag is an orally effective thrombopoietin receptor (TpoR) agonist. By activating TpoR, Totrombopag initiates an intracellular signaling cascade mediated by JAK2 kinase and the transcription factor Stat5, a signaling process that is the primary mechanism regulating megakaryocyte growth and differentiation into platelets. Totrombopag can be used to study platelet production and megakaryocyte biology[1].
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