Prostaglandin E2-1-glyceryl ester
CAS No. : 37497-47-5
(Synonyms: PGE2-1-glyceyl ester)
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| Cat. No. : | HY-114826 |
| M.Wt: | 426.54 |
| Formula: | C23H38O7 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Prostaglandin E2-1-glyceryl ester, a Prostaglandin Glycerol Ester, is an endocannabinoid ligand for the CB1 receptor. Prostaglandin E2-1-glyceryl ester induces rapid, transient elevation of intracellular free Ca2+[1][2].
IC50 & Target:EC50: 150 nM (Ca2+ in NG108-15 cells)[2].
In Vitro: Prostaglandin E2-1-glyceryl ester is rapidly hydrolyzed in rat plasma to generate PGE2 (t1⁄2 = 14 s) but is only slowly metabolized in human plasma (t1⁄2 = 10 min)[1].
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