CAY10602


CAS No. : 374922-43-7

374922-43-7
Price and Availability of CAS No. : 374922-43-7
Size Price Stock
10mg $50 In-stock
25mg $115 In-stock
50mg $200 In-stock
100mg $340 In-stock
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Cat. No. : HY-104073
M.Wt: 418.44
Formula: C22H15FN4O2S
Purity: >98 %
Solubility: DMSO : 41.67 mg/mL (ultrasonic)
Introduction of 374922-43-7 :

CAY10602 is a SIRT1 activator. CAY10602 dose-dependently suppresses the NF-κB-dependent induction of TNF-α by lipopolysaccharide in THP-1 cells[1]. IC50 & Target: SIRT1[1] In Vitro: Compounds (including CAY10602/compound 1) with SIRT1-activating properties have a significant effect on fat mobilization in differentiated adipocytes, and these compounds (including CAY10602) have antiobesity and/or antidiabetic properties. Compounds (including CAY10602) with SIRT1 activating potential exert strong suppression of TNF-α release at concentrations between 20 and 60 μM[1].

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