Kisspeptin-10, human
CAS No. : 374675-21-5
| Size | Price | Stock |
|---|---|---|
| 1mg | $75 | In-stock |
| 5mg | $180 | In-stock |
| 10mg | $290 | In-stock |
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| Cat. No. : | HY-P0254 |
| M.Wt: | 1302.44 |
| Formula: | C63H83N17O14 |
| Purity: | >98 % |
| Solubility: | H2O : ≥ 25 mg/mL |
Kisspeptin-10, human is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10, human acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role in embryonic kidney development. Kisspeptin-10/GPR54 signaling induces osteoblast differentiation via NFATc4-mediated BMP2 expression[1].
IC50 & Target:GPR54[1]
Angiogenesis[1]
In Vitro: Kisspeptin-10 (KP-10) and its receptor GPR54 are key components in the regulation of GnRH secretion in humans and other mammals. Kisspeptin-10 protein binds to GPR54. Activation of Kisspeptin-10 suppresses pulmonary human melanoma and Kisspeptin-10 is a metastasis suppressor in breast cancer cells[1].
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