2-Dimethylaminophenol


CAS No. : 3743-22-4

3743-22-4
Price and Availability of CAS No. : 3743-22-4
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Cat. No. : HY-34005
M.Wt: 137.18
Formula: C8H11NO
Purity: >98 %
Solubility:
Introduction of 3743-22-4 :

2-Dimethylaminophenol is an inhibitor of human glyoxalase 1 (GLO1). 2-Dimethylaminophenol disrupts metal binding by substituting the pyridine nitrogen donor with a dimethylamino group[1]. In Vitro:2-Dimethylaminophenol (Compound 31) (200 μM; 30 min) shows no significant inhibitory effect on recombinant human MMP-2 at the concentration of 200 μM[1].
2-Dimethylaminophenol (200 μM; 15-20 min) inhibits the activity of recombinant human GLO1 by 36% at a concentration of 200 μM[1].
2-Dimethylaminophenol (200 μM; 15 min) exerts no significant inhibitory effect on recombinant human hCAII at the concentration of 200 μM[1].

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