MitoBloCK-1


CAS No. : 373370-73-1

(Synonyms: MB-1)

373370-73-1
Price and Availability of CAS No. : 373370-73-1
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5mg $915 In-stock
10mg $1465 In-stock
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100mg $5373 In-stock
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Cat. No. : HY-122658
M.Wt: 368.25
Formula: C14H14BrN3O2S
Purity: >98 %
Solubility:
Introduction of 373370-73-1 :

MitoBloCK-1 (MB-1) is an inhibitor that blocks the import of substrates that use the TIM22 import pathway. MitoBloCK-1 inhibits import by preventing binding of substrate to tim9/10 complex to the substrate, thus the substrate failed to be reach the TIM22 translocon. MitoBloCK-1 inhibits protein import of TIM22 substrates into mitochondria. MitoBloCK-1 attenuates the import of the carrier proteins including the ADP/ATP and phosphate carriers. MitoBloCK-1 also inhibits the import of an additional carrier protein, PiC, and the outer membrane protein Tom40[1][2].

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