3-Picolylamine


CAS No. : 3731-52-0

(Synonyms: Picolamine; 3-Pyridinemethanamine; Pyridin-3-ylmethanamine)

3731-52-0
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Cat. No. : HY-Y0047
M.Wt: 108.14
Formula: C6H8N2
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 3731-52-0 :

3-Picolylamine is a primary amine compound containing a pyridine ring structure. 3-Picolylamine inhibits histaminase (diamine oxidase) activity in pig kidneys. 3-Picolylamine significantly enhances the contractile response of isolated guinea pig ileum to Histamine (HY-B1204). 3-Picolylamine can be used to study histamine-related physiological mechanisms or allergic diseases (such as histamine-mediated inflammatory responses)[1][2]. In Vitro:3-picolylamine significantly potentiates the ileal contractile response to histamine[2].
3-Picolylamine inhibits the oxidation of cadaverine and histamine by porcine kidney histaminase with an IC50 of approximately 133 µM[2].

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