PI3K/mTOR-IN-23
CAS No. : 371943-05-4
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| Cat. No. : | HY-109633 |
| M.Wt: | 313.37 |
| Formula: | C16H15N3O2S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
PI3K-IN-18 is a dual inhibitor of PI3K and mTOR with IC50 values of 49 and 41 nM. PI3K-IN-18 inhibits cancer cells proliferation[1].
In Vitro: PI3K-IN-18 (Compound 1) acts as a dual inhibitor of mTOR and PI3K-α in recombinant enzyme assays, with an mTOR IC50 of 49 nM, a PI3K-α IC50 of 41 nM[1].
PI3K-IN-18 inhibits LNCaP cell proliferation with an IC50 of 1300 nM[1].
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- PI3K/mTOR-IN-23
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