Azlocillin (sodium salt)


CAS No. : 37091-65-9

(Synonyms: Sodium azlocillin)

37091-65-9
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Cat. No. : HY-B0529A
M.Wt: 483.47
Formula: C20H22N5NaO6S
Purity: >98 %
Solubility: H2O : 6.67 mg/mL (ultrasonic);DMSO : 100 mg/mL (ultrasonic)
Introduction of 37091-65-9 :

Azlocillin sodium salt (Sodium azlocillin), a semisynthetic penicillin, is a broad spectrum β-lactam antibiotic. Azlocillin sodium salt shows antipseudomonal activity, and also potent against the malarial parasite Plasmodium falciparum[1][2][3]. IC50 & Target: Bacteria[1] In Vitro: Over 75% of the isolates of Pseudomonas aeruginosa are inhibited by Azlocillin at a concentration of 12.5 μg/mL. Azlocillin is also active against indole-negative and -positive Proteus spp., inhibiting 98% and 71%, respectively, at a concentration of 12.5 μg/mL. Gram-positive cocci except penicillin G-resistant Staphylococcus aureus are susceptible to Azlocillin[1]. In Vivo: Azlocillin (75 mg/kg) treatment increases the survival of neutropenic mice infected with Escherichia coli or Klebsiella pneumoniae[2].

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