Zinterol


CAS No. : 37000-20-7

(Synonyms: MJ 9184)

37000-20-7
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Cat. No. : HY-14304
M.Wt: 378.49
Formula: C19H26N2O4S
Purity: >98 %
Solubility:
Introduction of 37000-20-7 :

Zinterol (MJ 9184) is a potent and selective β2-adrenoceptor agonist[1]. Zinterol increases ICa in a concentration-dependent manner with an EC50 of 2.2 nM[2]. IC50 & Target:β2-adrenoceptor[1] In Vivo:Zinterol (2.5 μg/kg i.v. bolus over 5 s) leads to ventricular arrhythmias including premature ventricular complexes (PVCs) and runs of ventricular tachycardia (VT) in heart failure (HF) rabbits. Zinterol at a lower dose (1 μg/kg i.v, n=4) does not induce ventricular arrhythmias in HF rabbits[3].

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