Chlorhexidine (dihydrochloride)
CAS No. : 3697-42-5
| Size | Price | Stock |
|---|---|---|
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| 10g | $43 | In-stock |
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| Cat. No. : | HY-B1145 |
| M.Wt: | 578.37 |
| Formula: | C22H32Cl4N10 |
| Purity: | >98 % |
| Solubility: | DMSO : 14 mg/mL (ultrasonic) |
Chlorhexidine dihydrochloride is an orally active antimicrobial agent. Chlorhexidine dihydrochloride can damage the bacteria cell wall, inhibit proliferation of S. sobrinus and induce DNA damage[1][2][3].
In Vitro:Chlorhexidine dihydrochloride (100-200 μM, 15-240 min) causes clear dose-dependent reduction of S. aureus viability[1].
Chlorhexidine dihydrochloride (1.25-20 μM, 24 h) inhibites the growth of human gingival fibroblast[2].
In Vivo:Chlorhexidine dihydrochloride (0.5 ml of 0.12% chlorhexidine digluconate, orally, twice daily for 8 days) caused DNA damage in rats[1].
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