Meclofenoxate (hydrochloride)
CAS No. : 3685-84-5
(Synonyms: Centrophenoxine (hydrochloride))
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| Cat. No. : | HY-17555 |
| M.Wt: | 294.17 |
| Formula: | C12H17Cl2NO3 |
| Purity: | >98 % |
| Solubility: | H2O : 33.33 mg/mL (ultrasonic);DMSO : ≥ 50 mg/mL |
Meclofenoxate (Centrophenoxine) hydrochloride is an ester synthesized from DMAE and pCPA, capable of crossing the blood-brain barrier, and can stimulate memory and enhance cognition[1][2][3]. In Vitro:Meclofenoxate Hydrochloride (10 µM, 24 hours) significantly protects mitochondrial function in primary neurons, restoring mitochondrial morphology, reversing Rotenone (HY-B1756)-induced mitochondrial damage, and regulating redox balance[3]. In Vivo:Meclofenoxate Hydrochloride (50 µg/g, i.p., once daily for 4 weeks) significantly improved behavioral abnormalities and depression-like symptoms in rotenone (HY-B1756)-induced Parkinson's disease mice[3].
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