MST-312


CAS No. : 368449-04-1

(Synonyms: Telomerase Inhibitor IX)

368449-04-1
Price and Availability of CAS No. : 368449-04-1
Size Price Stock
5mg $55 In-stock
10mg $90 In-stock
25mg $180 In-stock
50mg $280 In-stock
100mg $450 In-stock
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Cat. No. : HY-120145
M.Wt: 380.35
Formula: C20H16N2O6
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic)
Introduction of 368449-04-1 :

MST-312 is a telomerase inhibitor. MST-312 is a chemically modified derivative of green tea epigallocatechin gallate (EGCG). MST-312 can be used for the research of cancer, such as multiple myeloma (MM)[1]. IC50 & Target: telomeras[1] In Vitro: MST-312 (2~8 μM; 0~72 hours; U-266 cells) reduces cellular viability in a dose dependent and time-dependent manner[1].
MST-312 (2~8 μM; 48 hours; U-266 cells) induces cell apoptosis in a dose-dependent manner[1].
MST-312 (2 μM; 48 hours; U-266 cells) up-regulates the pro-apoptotic gene Bax and down-regulates the anti-apoptotic gene Bcl-2 and suppresses the expression of c-Myc and hTERT genes[1].

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