| Size | Price | Stock |
|---|---|---|
| 1mg | $90 | In-stock |
| 5mg | $240 | In-stock |
| 10mg | $390 | In-stock |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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| Cat. No. : | HY-N2230 |
| M.Wt: | 283.33 |
| Formula: | C17H17NO3 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
N-p-trans-Coumaroyltyramine is a natural phenolic amide compound and an inhibitor of AChE (IC50: 122 μM) and α-glucosidase (IC50: 2.7 μM). N-p-trans-Coumaroyltyramine also has anti-trypanosomal activity, with an IC50 of 13.3 µM against T. brucei rhodesiense. N-p-trans-Coumaroyltyramine can be used in the research of diseases such as Alzheimer's disease[1][2][3].
IC50 & Target:IC50: 122 μM (AChE)[2]
In Vitro:N-p-trans-Coumaroyltyramine is cytotoxic to rat skeletal muscle myoblasts (L6 cells), with an IC50 of 105.3 μM[1].
N-p-trans-Coumaroyltyramine (0-120 μg/mL; 0-60 min) inhibits AChE activity in a dose-dependent manner, and the inhibition mode is reversible and mixed (competitive/non-competitive)[2].
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