YL-109
CAS No. : 36341-25-0
| Size | Price | Stock |
|---|---|---|
| 5mg | $55 | In-stock |
| 10mg | $90 | In-stock |
| 25mg | $150 | In-stock |
| 50mg | $250 | In-stock |
| 100mg | $350 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-18619 |
| M.Wt: | 257.31 |
| Formula: | C14H11NO2S |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
YL-109 is an antitumor agent that can induce carboxyl terminus of Hsp70-interacting protein (CHIP) expression through aryl hydrocarbon receptor (AhR) signaling. YL-109 has ability to inhibit breast cancer cell growth and invasiveness[1].
In Vitro: YL-109 (0.001-10 μM; 96 h or 24 h) inhibits cell proliferation, motility, and invasiveness in breast cancer cells[1].
YL-109 (1 μM) increases both CHIP mRNA and protein levels in MDA-MB-231 cells[1].
In Vivo: YL-109 (15 mg/kg; s.c. for every 2 d) inhibits both tumor growth and cancer metastasis of breast cancer cells in vivo[1].
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