SSR182289
CAS No. : 363151-21-7
(Synonyms: SSR182289A (free base))
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| Cat. No. : | HY-19674 |
| M.Wt: | 597.68 |
| Formula: | C30H33F2N5O4S |
| Purity: | >98 % |
| Solubility: |
SSR182289 (SSR182289A free base) is a selective and potent orally active thrombin inhibitor. SSR182289 competitively and selectivity inhibits human thrombin (Ki=0.031 μM). SSR182289 demonstrates anticoagulant activity in vitro (thrombin time EC100=96 nM) and inhibits tissue factor-induced thrombin generation (IC50=0.15 μM) in human plasma. SSR182289 inhibits thrombin-induced aggregation of human platelets (IC50=32 nM), but has no effect on aggregation induced by other platelet agonists [1][2].
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