Propiomazine


CAS No. : 362-29-8

362-29-8
Price and Availability of CAS No. : 362-29-8
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1mg $293 In-stock
5mg $720 In-stock
10mg $987 In-stock
25mg $1520 In-stock
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Cat. No. : HY-U00051
M.Wt: 340.48
Formula: C20H24N2OS
Purity: >98 %
Solubility: DMSO : 83.33 mg/mL (ultrasonic)
Introduction of 362-29-8 :

Propiomazine is an orally active antihistamine agent. Propiomazine is a potent prolactin (PRL) release stimulant, whose effect depends on the antagonism of the dopaminergic system and can inhibit the secretion of luteinizing hormone (LH). Propiomazine is mainly used for anesthesia assistance, mental disorders and anxiety-induced sedation, and can also be used in research related to insomnia[1][2][3][4]. In Vivo:Propiomazine (0.2 mg/kg, nasal administration, rats) is quickly absorbed, followed by rapid reduction of the plasma concentrations[3].
Propiomazine (25 mg/kg, i.p., at 0 and 3 h after challenge) protects rats against CCl4-induced hepatic injury[4].
Propiomazine (0.31-20 mg/kg, i.v.) increases plasma prolactin concentrations in rats[5].

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