L-Phenylalanyl-L-glutamic acid


CAS No. : 3617-45-6

(Synonyms: H-Phe-Glu-OH)

3617-45-6
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Cat. No. : HY-114844
M.Wt: 294.30
Formula: C14H18N2O5
Purity: >98 %
Solubility: H2O : ≥ 100 mg/mL
Introduction of 3617-45-6 :

L-Phenylalanyl-L-glutamic acid (H-Phe-Glu-OH) is a dipeptide present in the exudates of alfalfa seedlings, which exhibits high affinity for PEPT2. L-Phenylalanyl-L-glutamic acid can serve as the peptide scaffold of a tyrosyl-tRNA synthetase inhibitor against Staphylococcus aureus[1][2][3]. In Vitro:L-Phenylalanyl-L-glutamic acid acts as a peptide scaffold inhibitor of Staphylococcus aureus tyrosyl-tRNA synthetase[1].
L-Phenylalanyl-L-glutamic acid is a high-affinity substrate of PEPT2 with a Ki of 0.022 mM; it exhibits low affinity for PEPT1, with a Ki of 0.18 mM[3].

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