Hydracarbazine
CAS No. : 3614-47-9
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| Cat. No. : | HY-121354 |
| M.Wt: | 153.14 |
| Formula: | C5H7N5O |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Hydracarbazine is a pyridazine. Hydracarbazine can effectively lower blood pressure, it can be used for the research of high blood pressure[1][2]. In Vivo:Hydracarbazine (1-4 mg/kg; i.v. once) induced in the dog, cat and rabbit hypotension by peripheral vasodilation, showed no inhibitory action on vasomotor centers and decreased the hypertensive effects of adrenaline, noradrenaline, 5-hydroxytryptamine, pituitrin, and splanchnic nerve stimulation[1]. Hydracarbazine (15-18 mg/kg; p.o. once daily) prevents the increased blood pressure and heart rate, reduces the renal histol and reduces the hypertensive syndrome with a combination of pempidine in high arterial pressure rats[2].
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