Dihydrosanguinarine
CAS No. : 3606-45-9
(Synonyms: 13,14-Dihydrosanguinarine)
| Size | Price | Stock |
|---|---|---|
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| 5mg | $230 | In-stock |
| 10mg | $380 | In-stock |
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| Cat. No. : | HY-N0902 |
| M.Wt: | 333.34 |
| Formula: | C20H15NO4 |
| Purity: | >98 % |
| Solubility: | DMSO : 5.2 mg/mL (ultrasonic;warming) |
Dihydrosanguinarine is a natural compound isolated from the leaves of Macleaya microcarpa; has antifungal and anticancer activity. IC50 value: Target: in vitro: Dihydrosanguinarine showed much less cytotoxicity than sanguinarine: at the highest concentration tested (20 microM) and 24h exposure, dihydrosanguinarine decreased viability only to 52% [1]. Dihydrosanguinarine showed the highest antifungal activity against B. cinerea Pers, with 95.16% mycelial growth inhibition at 50 μg/ml [2]. dihydrosanguinarine showed the most potent leishmanicidal activities (IC(50) value: 0.014 microg/ml, respectively) [4]. in vivo: Repeated dosing of DHSG for 90 days at up to 500 ppm in the diet (i.e. approximately 58 mg/kg/day) showed no evidence of toxicity in contrast to results published in the literature [3].
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