Seletracetam


CAS No. : 357336-74-4

(Synonyms: Ucb 44212)

357336-74-4
Price and Availability of CAS No. : 357336-74-4
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Cat. No. : HY-119810
M.Wt: 232.23
Formula: C10H14F2N2O2
Purity: >98 %
Solubility: DMSO : 200 mg/mL (ultrasonic)
Introduction of 357336-74-4 :

Seletracetam (Ucb 44212), as an analog of the antiepileptic agent Levetiracetam, is a SV2A modulator for the research of epilepsy[1][2][3]. IC50 & Target: SV2A[1] In Vitro: Seletracetam decreases seizure activity in a number of epilepsy models and binds to the synaptic vesicle protein SV2A[2].
Seletracetam decreases synaptic responses in a time-, frequency- and concentration-dependent manner[2].
Seletracetam modifies rates of presynaptic release[2].
Seletracetam inhibits high-voltage-activated Ca2+ currents and intracellular Ca2+ increase in rat cortical neurons in vitro[3].

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