Anticonvulsant agent 1


CAS No. : 357336-17-5

(Synonyms: 4-(2,2-Difluoroethenyl)-α-ethyl-2-oxo-1-pyrrolidineacetamide)

357336-17-5
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Cat. No. : HY-U00348
M.Wt: 232.23
Formula: C10H14F2N2O2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 357336-17-5 :

Anticonvulsant agent 1 is an anticonvulsant agent extracted from patent WO2001062726A2, Compound 156. In Vitro: The inhibition constant (Ki) of Anticonvulsant agent 1 (Compound 156) is determined in competitive binding experiments by measuring the binding of a single concentration of a radioactive ligand at equilibrium with various concentrations of the unlabeled test substance. The concentration of the test substance inhibiting 50 % of the specific binding of the radioligand is called the IC50. The equilibrium dissociation constant Ki is proportional to the IC50 and is calculated. Anticonvulsant agent 1 shows pKi values of 6.0 and greater[1]

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