Anxiolytic/nonsedative agent-1
CAS No. : 355022-97-8
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| Cat. No. : | HY-103521 |
| M.Wt: | 337.33 |
| Formula: | C18H15N3O4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Anxiolytic/nonsedative agent-1 (compound 2b) is a potent and selective GABAA agonist. Anxiolytic/nonsedative agent-1 shows appreciable affinity for the BzR in bovine brain membranes with Kis of 14, 121, 239 nM for α1β2γ2, α2β2γ2, α5β3γ2, respectively. Anxiolytic/nonsedative agent-1 shows α2 selective efficacy in vitro and anxioselective effects in vivo[1].
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