Perfluorohexane


CAS No. : 355-42-0

(Synonyms: AF-0150)

355-42-0
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Cat. No. : HY-109540
M.Wt: 338.04
Formula: C6F14
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 355-42-0 :

Perfluorohexane (AF-0150) is a perfluorocarbon. Perfluorohexane is also an enhancer of high-intensity focused ultrasound (HIFU) therapy. Perfluorohexane increases HO-1 and IL-10. Perfluorohexane exerts an antioxidant effect. Perfluorohexane alleviates lung injury induced by LPS (HY-D1056A1). Perfluorohexane improves the efficiency and precision of treatment and reduces damage to surrounding normal tissues. Perfluorohexane can be used in the study of acute lung injury[1][2][3]. In Vitro:Perfluorohexane (12-36 h) shows no cytotoxicity to human mesothelial cells, does not induce cell activation, and does not significantly affect the expression of cell adhesion molecules ICAM-1, VCAM-1 and surfactant protein A[1].
In Vivo:Perfluorohexane (10 mL/kg; i.p.; every 2 h) attenuates Lipopolysaccharide (HY-D1056A1)-induced lung injury in rats[3].

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