Estradiol (hemihydrate)
CAS No. : 35380-71-3
(Synonyms: β-Estradiol (hemihydrate); 17β-Estradiol (hemihydrate); 17β-Oestradiol (hemihydrate);)
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| Cat. No. : | HY-B0141C |
| M.Wt: | 281.39 |
| Formula: | C18H24O2·1/2H2O |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Estradiol (β-Estradiol) hemihydrate is a steroid hormone and the major female sex hormone. Estradiol (β-Estradiol) hemihydrate can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol (β-Estradiol) hemihydrate can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering[1][2]. In Vitro: Estradiol hemihydrate (10 nM, 7 days) induces neural differentiation and increased neurite branching of human endometrial stem cells (hEnSCs)[1]. Estradiol hemihydrate (17β-estradiol, 10 nM, 7 days) increases the expression of neuron-like cell markers (Tuj-1, nestin and NF-H) in neural-like cells differentiated from hEnSCs[1]. In Vivo: Estradiol hemihydrate (1 nM, the hippocampal slices from FBN-ARO-KO mice) rescues long-term potentiation (LTP) amplitude[1]. Estradiol hemihydrate (0.0167 mg, implanted s.c., FBN-ARO-KO mice) rescues the molecular and functional deficits in FBN-ARO-KO mice[1].
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