HBED (dihydrochloride)
CAS No. : 35369-53-0
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| Cat. No. : | HY-W035520 |
| M.Wt: | 461.34 |
| Formula: | C20H26Cl2N2O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
HBED dihydrochloride is an orally active and hexadentate phenolic aminocarboxylate iron chelator. HBED refers to N, N'-bis(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid, inducing iron excretion in primates. HBED dihydrochloride has the potential to be used as an alternative to desferriamine for iron chelation therapy[1]. In Vivo:HBED monohydrochloride dihydrate produces different activity under different dosing methods. HBED does not produce significant effects when administered orally at doses of 81, 162, and 324 μMol/kg. After subcutaneous administration of 162 and 324 μMol/kg, the net iron excretion is increased[1].
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