Emeramide
CAS No. : 351994-94-0
(Synonyms: NBMI; BDTH2)
| Size | Price | Stock |
|---|---|---|
| 100mg | $40 | In-stock |
| 500mg | $95 | In-stock |
| 1g | $155 | In-stock |
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| 10 g | Get quote | |
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| Cat. No. : | HY-16739 |
| M.Wt: | 284.40 |
| Formula: | C12H16N2O2S2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic;warming);H2O : < 0.1 mg/mL |
Emeramide is a thiol-redox antioxidant and heavy metal chelator[1].
In Vitro: Emeramide (50 μM, 1 h) protects cell from Bleomycin (HY-108345)-induced cell (BPAECs) morphology alterations and cytotoxicity, and inhibits ROS generation, attenuates the Bleomycin-induced loss of cellular total thiols[2].
Emeramide (0-100 μM, pretreated for 24 h) inhibits Pb-induced neuroinflammation by reducing IL-1β and GFAP expression levels in U-87 MG cells[3].
In Vivo: Emeramide (450 mg/kg, daily, p.o., 6 weeks) decreases iron accumulation in Hfe H67D mutant mice ( a mouse model of brain iron accumulation)[4].
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