TRPM4-IN-1
CAS No. : 351424-20-9
(Synonyms: CBA)
| Size | Price | Stock |
|---|---|---|
| 5mg | $49 | In-stock |
| 10mg | $77 | In-stock |
| 25mg | $165 | In-stock |
| 50mg | $275 | In-stock |
| 100mg | $440 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-122605 |
| M.Wt: | 340.16 |
| Formula: | C15H11Cl2NO4 |
| Purity: | >98 % |
| Solubility: | DMSO : 83.33 mg/mL (ultrasonic) |
TRPM4-IN-1 (CBA) is a potent and selective inhibitor of the cation channel TRPM4, with an IC50 of 1.5 μM. TRPM4-IN-1 can be used for the research of cardiac diseases and prostate cancer[1][2].
In Vitro: TRPM4-IN-1 (compound 5) is a potent and selective inhibitor of TRPM4 current in TRPM4 overexpressed HEK293 cells[1].
TRPM4-IN-1 reversibly blocks endogenous TRPM4 currents in LNCaP (prostate cancer) cells[1].
TRPM4-IN-1 (50 μM; Overnight) restores functional expression of A432T, a loss‐of‐expression TRPM4 variant[1].
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