Timepidium bromide
CAS No. : 35035-05-3
(Synonyms: Sesden; SA504)
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| Cat. No. : | HY-U00184 |
| M.Wt: | 400.40 |
| Formula: | C17H22BrNOS2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Timepidium bromide (Sesden; SA504) is an anticholinergic agent. IC50 & Target: Cholinergic[1] In Vivo: Effects of Timepidium bromide (TB), acetylcholine (ACh) and neostigmine (Neost) on gastric and duodenal blood flow distribution are studied by the use of 131I-labeled macroaggregated human serum albumin (MAA) in rabbits. In normal rabbits, gastric blood flow is found to be uneven in various regions of the stomach: anterior corpus (50% of total gastric blood flow) greater than posterior corpus (40%) greater than pyloric antrum (7%). Intravenous administration of Timepidium bromide (200 μg/kg) to normal rabbits produces a slight increase in total gastric blood flow, but the increase in the mucosal layer of the pyloric antrum is considerable[1].
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