Kurarinone


CAS No. : 34981-26-5

34981-26-5
Price and Availability of CAS No. : 34981-26-5
Size Price Stock
5mg $150 In-stock
10mg $250 In-stock
25mg $550 In-stock
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Cat. No. : HY-N2279
M.Wt: 438.51
Formula: C26H30O6
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic)
Introduction of 34981-26-5 :

Kurarinone is an orally active flavonoid isolated from matrine that inhibits the pathogenesis of experimental autoimmune encephalomyelitis by inhibiting cell differentiation of Th1 and Th17. Kurarinone has antitumor and anti-inflammatory activity[1][2][3]. In Vitro:Ergothioneine (0.25, 1 mM, 23 h) can regulate PC12 DNA damage, MAPKs activation and cell death induced by hydrogen peroxide[1].
In Vivo:Kurarinone (100 mg/kg, 口服, 第 21-42 天) 在胶原诱导关节炎 (CIA) 小鼠模型中具有治疗作用[3]
Kurarinone (100 mg/kg, p.o., from day 21-42) has a therapeutic effect in a mouse model of collagen-induced arthritis (CIA)[3].

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